反应详情

1-Phenyl-2,3-naphthalenedicarboxylic anhydride (3.0 g) and cyclopropylamine (5 ml) were shaken for 5 minutes. The reaction mixture became very warm and excess cyclopropylamine was evaporated in vacuo. The solid remaining was then heated at 220° to 240° for 5 minutes in a nitrogen atmosphere. The solid formed was allowed to cool and was recrystallised from light petroleum (b.p. 40°-60°)/chloroform to give 2-cyclopropyl-1,3-dioxo-4-phenylbenz[f]isoindoline, (2.7 g, m.p. 198°).

1. temperatureThe reaction mixture became very warm
2. customexcess cyclopropylamine was evaporated in vacuo
3. temperatureThe solid remaining was then heated at 220° to 240° for 5 minutes in a nitrogen atmosphere
4. customThe solid formed
5. temperatureto cool
6. customwas recrystallised from light petroleum (b.p. 40°-60°)/chloroform