Water → HCID 12953785, compound

Participants

Reaction Steps

The above carboxylic acid (11 g) in THF (150 ml) was added to lithium aluminium hydride (6.0 g) in THF (150 ml) over 0.5 hr. The reaction mixture was stirred for 2 hr. and water was carefully added. The resultant slurry was washed with ether (3×100 ml) and the combined ethereal washings were dried (magnesium sulphate) and evaporated to dryness to give 2-hydroxymethyl-3-(1'-hydroxypropyl)naphthalene as an oil; a small portion was recrystallised from light petroleum (b.p. 60°-80°)/chloroform to give a crystalline solid, m.p. 70°.

Provenance & Evidence