Malonic Acid → 2-Acetylbenzoic acid

HRID 1703191Notes

Reaction equation

[C:1]1(=[O:11])[O:6][C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12](O)(=O)CC(O)=O>>[O:5]=[C:4]([C:3]1[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=1[C:1]([OH:6])=[O:11])[CH3:12]

Participants

Reactant 2

HCID 867Malonic Acid

HCID 6811Phthalic Anhydride

Product 1

HCID 684742-Acetylbenzoic acid

Procedure

(i) Using the method of Preparation 3, phthalic anhydride and malonic acid gave 2-(1'-oxoethyl)benzoic acid (m.p. 110°) and thence 1-hydroxymethyl-2-(1'-hydroxyethyl)benzene (oil)

Sources & evidence

ORD record: ord-3b729435e6ec4e9d91fedc16d48f0b6b
Source dataset: uspto-grants-1982_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04351842

Reaction notes

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