HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 3-[2,4-Bis(diethylamino)phenyl]-3-(1-n-octyl-2-methyl-3-indolyl)phthalide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | N~1~,N~1~,N~3~,N~3~-Tetraethylbenzene-1,3-diamine | HCID 19382815 | — |
| Reactant | 2-(2-Methyl-1-octyl-1H-indole-3-carbonyl)benzoic acid | HCID 19763802 | — |
| Product | 3-[2,4-Bis(diethylamino)phenyl]-3-(1-n-octyl-2-methyl-3-indolyl)phthalide | HCID 20523552 | — |
Reaction Steps
Proceeding in a manner similar to that described in part B of Example 5 above, 2.34 g (0.006 mole) of 2-[(1-n-octyl-2-methyl-3-indolyl)carbonyl]benzoic acid prepared according to Example 5, part A, and 2.40 g of N,N,N',N'-tetraethyl-m-phenylenediamine were interacted in the presence of 2.40 g of acetic anhydride to obtain 3-[2,4-bis(diethylamino)phenyl]-3-(1-n-octyl-2-methyl-3-indolyl)phthalide (Formula III: R0 =R1 =R2 =R3 =Y1 =H; R=CH2CH3 ; R4 =N(CH2CH3)2 ; R5 =CH3 ; R6 =(CH2)7CH3) as a tar-like semisolid. A toluene solution of this material developed a purple color when spotted on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04351768 |
| Source dataset | uspto-grants-1982_09 |
| ORD ID | ord-d60d6d178399431b9cfd3261d91c7292 |
| Source note | uspto-grants-1982_09 |