methyl 1H-pyrrole-3-carboxylate → Methyl 5-(3-fluorophenylthio)pyrrole-3-carboxylate

HRID 1703265Notes

Reaction equation

HRID 1703265 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([S:8]Cl)[CH:5]=[CH:6][CH:7]=1.[NH:10]1[CH:14]=[CH:13][C:12]([C:15]([O:17][CH3:18])=[O:16])=[CH:11]1>>[F:1][C:2]1[CH:3]=[C:4]([S:8][C:14]2[NH:10][CH:11]=[C:12]([C:15]([O:17][CH3:18])=[O:16])[CH:13]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 12361759methyl 1H-pyrrole-3-carboxylateHCID 20401071HCID 20401071, compound

Product 1

HCID 20401056Methyl 5-(3-fluorophenylthio)pyrrole-3-carboxylate

Procedure

By the same procedure, m-fluorobenzenesulfenyl chloride is reacted with methyl pyrrole-3-carboxylate to form methyl 5-(3-fluorophenylthio)pyrrole-3-carboxylate.

Sources & evidence

ORD record
ord-27b2ca62afcc4e8482f7704f02e70002
Source dataset
uspto-grants-1982_09
Patent number
US04351843

Reaction notes

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