HCID 12928229, compound → HCID 12928230, compound

Participants

Reaction Steps

In 30 ml of ethanol, 2.14 g (0.0070 mol) of ethyl 2-azido-3-methyl-4,5-dichloro-4,5,5-trifluoropentanoate and 0.61 g of 5% palladium-containing activated carbon were placed and bubbled with hydrogen gas (at a flow rate of 15 ml/min) for 22 hours. Consequently there was obtained 1.04 g (0.0037 mol, yield of 53% of ethyl 2-amino-3-methyl-4,5-dichloro-4,5,5-trifluoropentanoate having b.p. 71° C./2 mm, nD20 1.4328, νNH2 3398 and 3327 cm-1 and νC=O 1740 cm-1.

Provenance & Evidence