反应详情

To 500 ml. of methylethylketone is added 0.1 mole of 4-amino-2-chloro-7,8-dimethoxyquinazoline and 0.12 mole of morpholine and the mixture is refluxed overnight. After cooling in ice-water the solid precipitated is collected by filtration, washed with ether and air dried to obtain the title compound.

1. temperaturethe mixture is refluxed overnight
2. customprecipitated
3. filtrationis collected by filtration
4. washwashed with ether and air
5. customdried