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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1703411Generated: November 1, 2026

M-Cresol → Salicyl Alcohol

https://huagongshe.com/reaction/1703411

Reaction equation

Participants

RoleNameHCIDCharge
ReactantM-CresolHCID 342—
ReactantFormaldehydeHCID 712—
ReactantPhenolHCID 996—
Reactant3-EthylphenolHCID 12101—
CatalystZinc AcetateHCID 11192—
CatalystCadmium formateHCID 197815—
ProductSalicyl AlcoholHCID 5146—

Reaction Steps

Marchand and Grenet U.S. Pat. Nos. 3,290,352 and 3,290,393, patented Dec. 6, 1966, note that British Pat. No. 774,696 condenses phenol, meta-cresol or meta-ethylphenol with formaldehyde in aqueous medium in the presence of zinc acetate or cadmium formate. Starting with phenol, the best yield of pure saligenol obtained is 21%.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04351962
Source datasetuspto-grants-1982_09
ORD IDord-0fda863c31754c88be9ce0e0fa6edb63
Source noteuspto-grants-1982_09