HCID 22761662, compound → HCID 22761652, compound

Participants

Reaction Steps

The mixture of 3.0 g of N-(4-nitro-2-hydroxymethylphenyl)-4-chlorophthalimide, 1.5 g of Raney nickel and 250 ml of ethyl acetate is hydrogenated at room temperature and atmospheric pressure until the hydrogen uptake ceases. It is filtered, the filtrate evaporated and the residue recrystallized from ethyl acetate-diethyl ether, to yield the N-(4-amino-2-hydroxymethylphenyl)-4-chlorophthalimide melting at 228°-230°.

Provenance & Evidence