L-Malic Acid → HCID 131711319, compound
Reaction equation
[C:1]([OH:9])(=[O:8])[C@H:2]([CH2:4][C:5]([OH:7])=[O:6])[OH:3].C(=O)(O)[O-].[K+:14]>O>[OH2:3].[C:1]([O-:9])(=[O:8])[C@H:2]([CH2:4][C:5]([OH:7])=[O:6])[OH:3].[K+:14]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 10 °C
Procedure
134.1 g (one mole) of L-malic acid and 120 g (1.20 moles) of potassium bicarbonate are dissolved at 60° C. in 200 ml of water. The solution (pH 4.4) is concentrated under reduced pressure to make the total volume thereof about 200 ml. The concentrated solution is cooled to 10° C., and the mixture obtained (i.e., the mixture of the concentrated solution and crystals precipitated) is stirred at the same temperature for 4 hours. After stirring, the mixture had a pH of 6.0. The crystalline precipitates are collected by filtration. 144.6 g of monopotassium L-malate monohydrate are obtained as crystals. Yield: 76%
Workup
- concentrationThe solution (pH 4.4) is concentrated under reduced pressure
- customthe mixture obtained (i.e.
- additionthe mixture of the concentrated solution and crystals
- customprecipitated)
- stirringAfter stirring
- customThe crystalline precipitates
- filtrationare collected by filtration
Sources & evidence
- ORD record
- ord-056fdca7a2394532b507e4b1b9e6030c
- Source dataset
- uspto-grants-1978_11
- Patent number
- US04124636
Reaction notes
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