Ethyl ketone → HCID 54502385, compound

Participants

Reaction Steps

A mixture of 10.0g of 2-ethyl-5-nitrobenzyl methyl ether, 10.38g of 3-pentanone, 0.23g of 2-naphthalene sulfonic acid, and 0.60g of 5% platinum on carbon catalyst was shaken under hydrogen for 2 hours at room temperature and for 4 hours at 48° C. to 60° C. The mixture was diluted with 200 ml of ether, filtered and the filtrate shaken with 2.5% aqueous sodium hydroxide, washed with water, filtered through sodium sulfate and stirred over magnesium sulfate. The filtered solution was concentrated under vacuum to yield 10.76 grams of an amber liquid, pure by glc and tlc analyses.

Provenance & Evidence