HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-Methylthiobenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Methylthiobenzoic acid | HCID 178425911 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-Methylthiobenzoyl chloride | HCID 15555005 | — |
Reaction Steps
A solution of 50 g. of 4-methylthiobenzoic acid in dichloromethane is treated with excess thionyl chloride at its reflux temperature until no acid remains (according to infrared spectral analysis). Distillation at reduced pressure (b.p. 140° C./0.2 mm. Hg) provides a clear liquid which gradually solidifies to provide 4-methylthiobenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04124725 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-33391affce5543a9a7a005afb8c1cc2a |
| Source note | uspto-grants-1978_11 |