HCID 53766659, compound → Caffeic Acid

Participants

Reaction Steps

Fraction 2a was chromatographed on #3 Whatman paper, eluting with butanol-acetic acid-water (6:1:4) to separate any remaining caffeic acid. The eluate was concentrated and chromatographed on #3 Whatman paper. Elution with ethyl formate-acetic acid-toluene (4:1:5) produced the two isomers of the dimer in the following amounts: 73 mg. of 3-hydroxy-4-(3',4'-dihydroxycinnamoyl)-cinnamic acid, decomp. 135°-140° C. and 68 mg. of 4-hydroxy-3-(3',4'-dihydroxycinnamoyl)-cinnamic acid, decomp. 135°-140° C. The structural identity of the compounds was confirmed using ultraviolet scanning and nuclear magnetic resonance (NMR).

Provenance & Evidence