HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 70544112, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Phthalimide | HCID 6809 | — |
| Reactant | Hydrazine | HCID 9321 | — |
| Reactant | 1,1-Bis(methylthio)-2-nitroethylene | HCID 83623 | — |
| Reactant | HCID 12923416 | HCID 12923416 | — |
| Reactant | Bromopropylphthalimide | HCID 21958088 | — |
| Reactant | HCID 178431727 | HCID 178431727 | — |
| Product | HCID 70544112 | HCID 70544112 | — |
Reaction Steps
The reaction of 4-methyloxazole-2-thiol (5.8 g) with 3-bromopropylphthalimide (13.4 g) using the conditions described in Example 19 afforded 4-methyl-2-(3-phthalimidopropylthio)oxazole (14 g), m.p. 92°-93° (ethanol-ether). (ii) Treatment of the phthalimide compound (3.0 g) with hydrazine (1.53 g) followed by reaction of the product directly with 1-nitro-2,2-bis-methylthioethylene (2.2g) and then with methylamine under the conditions described in Example 8 afforded the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04124717 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-5cece16ac16948ccadac82f9087bc778 |
| Source note | uspto-grants-1978_11 |