反应详情

1.7 g. of methylhydrazine is dissolved in 30 ml. of ethanol. 3.3 g. of 4-chloro-1-methylpyrazolo[3,4-d]pyrimidine is added portionwise. The mixture is refluxed for 30 minutes and then allowed to stand in the refigerator overnight. The mixture is filtered and the product, 1-methyl-4-(1-methylhydrazino)pyrazolo[3,4-d]pyrimidine, is recrystallized from ethanol-methanol, m.p. 213°-215° (yield 4.2 g.).

1. temperatureThe mixture is refluxed for 30 minutes
2. customto stand in the refigerator overnight
3. filtrationThe mixture is filtered
4. customthe product, 1-methyl-4-(1-methylhydrazino)pyrazolo[3,4-d]pyrimidine, is recrystallized from ethanol-methanol, m.p. 213°-215° (yield 4.2 g.)