Benzoic acid, 2-chloro-5-(chlorosulfonyl)- → HCID 20505868, compound

HRID 1703701Notes

Reaction equation

HRID 1703701 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([S:11](Cl)(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[CH2:15]([O:22][CH:23]1[CH2:28][CH2:27][CH2:26][NH:25][CH2:24]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][C:8]([S:11]([N:25]2[CH2:26][CH2:27][CH2:28][CH:23]([O:22][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:24]2)(=[O:13])=[O:12])=[CH:7][C:3]=1[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 67306Benzoic acid, 2-chloro-5-(chlorosulfonyl)-HCID 199606043-(Benzyloxy)piperidine

Product 1

HCID 20505868HCID 20505868, compound

Procedure

2-Chloro-5-chlorosulfonylbenzoic acid is reacted with 3-benzyloxypiperidine by the method of Example 1. Recrystallization from ether-hexane yields the product, m.p. 173°-174° C.

Workup

  1. customRecrystallization from ether-hexane
  2. customyields the product, m.p. 173°-174° C.

Sources & evidence

ORD record
ord-4e4be89d809b4dbaa2c13e8e634913d1
Source dataset
uspto-grants-1978_11
Patent number
US04124590

Reaction notes

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