Acetic Acid → N-phenylmaleamic acid benzyltrimethyl-ammonium salt

Participants

Reaction Steps

48.2 g (0.1 mole) of benzyltrimethylammonium hydroxide solution (34.7% in methanol) is added to 19.1 g (0.1 mole) of N-phenylmaleamic acid in 100 ml of methanol, and the reaction mixture is stirred for one hour at room temperature. The pH-value is adjusted to about 7.0 with acetic acid, and the solvent is removed in vacuo in a rotary evaporator to leave 36.8 g of N-phenylmaleamic acid benzyltrimethyl-ammonium salt in the form of yellow oil, which crystallises after prolonged standing.

Provenance & Evidence