Carbonate Ion → N2-(2-Methoxy-4-(4-methylpiperazin-1-yl)phenyl)-N4-(2-(pyrimidin-2-yl)phenyl)-5-(trifluoromethyl)pyridine-2,4-diamine
Reaction equation
[C:41](=[O:42])([O-:43])[O-:44].[CH3:25][O:26][c:27]1[c:28]([NH2:29])[cH:30][cH:31][c:32]([N:34]2[CH2:35][CH2:36][N:37]([CH3:40])[CH2:38][CH2:39]2)[cH:33]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:21]([F:22])([F:23])[F:24])[c:6]([NH:8][c:9]2[c:10](-[c:15]3[n:16][cH:17][cH:18][cH:19][n:20]3)[cH:11][cH:12][cH:13][cH:14]2)[cH:7]1.[Cs+:45].[Cs+:46].[O:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1.[O:55]=[C:56]([CH:57]=[CH:58][c:59]1[cH:60][cH:61][cH:62][cH:63][cH:64]1)[CH:65]=[CH:66][c:67]1[cH:68][cH:69][cH:70][cH:71][cH:72]1.[O:73]=[C:74]([CH:75]=[CH:76][c:77]1[cH:78][cH:79][cH:80][cH:81][cH:82]1)[CH:83]=[CH:84][c:85]1[cH:86][cH:87][cH:88][cH:89][cH:90]1.[O:91]=[C:92]([CH:93]=[CH:94][c:95]1[cH:96][cH:97][cH:98][cH:99][cH:100]1)[CH:101]=[CH:102][c:103]1[cH:104][cH:105][cH:106][cH:107][cH:108]1.[Pd:53].[Pd:54]>>[c:2]1([NH:29][c:28]2[c:27]([O:26][CH3:25])[cH:33][c:32]([N:34]3[CH2:35][CH2:36][N:37]([CH3:40])[CH2:38][CH2:39]3)[cH:31][cH:30]2)[n:3][cH:4][c:5]([C:21]([F:22])([F:23])[F:24])[c:6]([NH:8][c:9]2[c:10](-[c:15]3[n:16][cH:17][cH:18][cH:19][n:20]3)[cH:11][cH:12][cH:13][cH:14]2)[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-19bbe10d06b0495cbea05c245f94bd45
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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