HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 6-Hydroxy-3-hydroxycarbonyl-6-methyl-4-thiaundecanoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Monomethyl maleate | HCID 5354456 | — |
| Reactant | 2-Methyl-1-sulfanylheptan-2-OL | HCID 13506860 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 6-Hydroxy-3-hydroxycarbonyl-6-methyl-4-thiaundecanoic acid methyl ester | HCID 54484813 | — |
Reaction Steps
A mixture of 2.6 g of maleic acid monomethyl ester, 3.2 g of 2-hydroxy-2-methylheptane-1-thiol, 0.5 ml of pyridine and 120 ml of methylene chloride is stirred for 3 hours at 30°. After the usual working up, 6-hydroxy-3-hydroxycarbonyl-6-methyl-4-thiaundecanoic acid methyl ester is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04125622 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-4520ee23d3ef460297e77c666abd1836 |
| Source note | uspto-grants-1978_11 |