HCID 12906295, compound → HCID 22760676, compound

HRID 1703855Notes

Reaction equation

HRID 1703855 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH:16]([NH:20][C:21]([NH:23][CH3:24])=[S:22])([CH2:18][CH3:19])[CH3:17]>>[BrH:1].[CH:16]([N:20]=[C:21]1[N:23]([CH3:24])[C:3]([C:5]2[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=2)([OH:4])[CH2:2][S:22]1)([CH2:18][CH3:19])[CH3:17]

Participants

3

Reactant 2

HCID 12906295HCID 12906295, compoundHCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenone

Product 1

HCID 22760676HCID 22760676, compound

Procedure

4.7 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 2.19 g of 1-sec.-butyl-3-methylthiourea were reacted according to the prescription given in Example 23 and the crystals were filtered off. Melting point: 163° C. (decomposition).

Workup

  1. filtrationthe crystals were filtered off

Sources & evidence

ORD record
ord-957d98d2db1e4653863d9de774f4033e
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

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