Bromo-4'-chloro-3'-sulfamoylacetophenone → 59814-64-1

HRID 1703859Notes

Reaction equation

HRID 1703859 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH:16]1([NH:19][C:20]([NH:22][CH3:23])=[S:21])[CH2:18][CH2:17]1>>[BrH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:21][C:20](=[N:19][CH:16]3[CH2:18][CH2:17]3)[N:22]2[CH3:23])=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]

Participants

3

Reactant 2

HCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenoneHCID 19650396HCID 19650396, compound

Product 1

HCID 2276064859814-64-1

Procedure

4.15 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone were reacted with 1.95 g of 1-cyclopropyl-3-methylthiourea according to the prescription given in Example 23 and the oily precipitate was crystallized with diisopropyl ether. Colorless, crystalline solid body: melting point: 204° C. (decomposition).

Workup

  1. customthe oily precipitate was crystallized with diisopropyl ether

Sources & evidence

ORD record
ord-043768d652914048a59646f7cde5b5c1
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

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