Bromo-4'-chloro-3'-sulfamoylacetophenone → HCID 22760571, compound

HRID 1703860Notes

Reaction equation

HRID 1703860 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH:16]1([CH2:21][NH:22][C:23]([NH:25][CH3:26])=[S:24])[CH2:20][CH2:19][CH2:18][CH2:17]1>>[BrH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:24][C:23](=[N:22][CH2:21][CH:16]3[CH2:20][CH2:19][CH2:18][CH2:17]3)[N:25]2[CH3:26])=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]

Participants

3

Reactant 2

HCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenoneHCID 22760550HCID 22760550, compound

Product 1

HCID 22760571HCID 22760571, compound

Procedure

4.7 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone were reacted with 2.6 g of 1-cyclopentylmethyl-3-methylthiourea according to the prescription given in Example 23 and the colorless crystalline final product was filtered off. Melting point: 189° C. (decomposition).

Workup

  1. filtrationthe colorless crystalline final product was filtered off

Sources & evidence

ORD record
ord-a836703e5dd54c0886019e02e64c4c51
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

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