Bromo-4'-chloro-3'-sulfamoylacetophenone → HCID 22760546, compound

HRID 1703871Notes

Reaction equation

HRID 1703871 reaction equation
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:6]=1)=[O:4].[CH3:16][N:17]([CH3:25])[NH:18][C:19]([NH:21][CH:22]([CH3:24])[CH3:23])=[S:20]>>[BrH:1].[Cl:11][C:8]1[CH:9]=[CH:10][C:5]([C:3]2([OH:4])[CH2:2][S:20][C:19](=[N:21][CH:22]([CH3:24])[CH3:23])[N:18]2[N:17]([CH3:25])[CH3:16])=[CH:6][C:7]=1[S:12](=[O:15])(=[O:14])[NH2:13]

Participants

3

Reactant 2

HCID 12952390Bromo-4'-chloro-3'-sulfamoylacetophenoneHCID 22760525HCID 22760525, compound

Product 1

HCID 22760546HCID 22760546, compound

Procedure

4.7 g of 2-bromo-4'-chloro-3'-sulfamoylacetophenone and 2.4 g of 1,1-dimethyl-4-isopropylthiosemicarbazide were reacted according to the prescription of Example 23 and the crystalline end product was filtered off. Colorless crystals: melting point: 189° C. (decomposition).

Workup

  1. filtrationthe crystalline end product was filtered off

Sources & evidence

ORD record
ord-9c879f9d867044f6aca439e73a5a4b5a
Source dataset
uspto-grants-1978_11
Patent number
US04125614

Reaction notes

Loading…