HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 4-[4-Chloro-3-(3,4-methylenedioxybenzylsulfamoyl)-phenyl]-3-methyl-2-methylimino-1,3-thiazolidine-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzo-1,3-dioxole-5-methylamine | HCID 75799 | — |
| Reactant | 4-Chloro-3-chlorosulfonylphenyl-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide | HCID 22760489 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 4-[4-Chloro-3-(3,4-methylenedioxybenzylsulfamoyl)-phenyl]-3-methyl-2-methylimino-1,3-thiazolidine-4-ol | HCID 22760498 | — |
Reaction Steps
6.5 g of 4-(4-chloro-3-chlorosulfonylphenyl)-3-methyl-2-methylimino-1,3-thiazolidine-4-ol-hydrobromide were reacted as prescribed in Example 76 with 2.4 g of 3,4-methylenedioxybenzyl amine and 3.5 g of triethyl amine and worked up. Colorless crystals from isopropanol, melting point: 131°-132° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04125614 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-124c85b9eb824843a5437fabed7b3972 |
| Source note | uspto-grants-1978_11 |