Ethyl [p-(p-nitrophenoxy)phenyl]acetate → HCID 20392571, compound

HRID 1704015Notes

Reaction equation

HRID 1704015 reaction equation
[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][CH:14]=2)=[CH:8][CH:7]=1)[CH3:2]>C(O)C.[Pt]=O>[CH2:1]([O:3][C:4](=[O:22])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][C:13]2[CH:14]=[CH:15][C:16]([NH2:19])=[CH:17][CH:18]=2)=[CH:8][CH:7]=1)[CH3:2]

Participants

4

Reactant 1

HCID 20392616Ethyl [p-(p-nitrophenoxy)phenyl]acetate

Product 1

HCID 20392571HCID 20392571, compound

Reagents, catalysts & solvents 2

HCID 82844Platinum oxide (PtO)CatalystHCID 702EthanolSolvent

Procedure

A mixture of 7.5 g of ethyl[ p-(p-nitrophenoxy)phenyl]acetate and 200 mg of platinum oxide in 200 ml of ethanol is shaken under 45 lbs of hydrogen for one hour and then filtered through diatomaceous earth which is washed with 20 ml of ethanol. The combined filtrate and washings are concentrated to a yellow oil. Bulb-to-bulb distillation affords a pale yellow opaque oil, b.p. 176° at 0.1 mm.

Workup

  1. filtrationfiltered through diatomaceous earth which
  2. washis washed with 20 ml of ethanol
  3. concentrationThe combined filtrate and washings are concentrated to a yellow oil
  4. distillationBulb-to-bulb distillation
  5. customaffords a pale yellow opaque oil, b.p. 176° at 0.1 mm

Sources & evidence

ORD record
ord-cb1d8de669fc485e8b52c7afe79f7fe0
Source dataset
uspto-grants-1978_11
Patent number
US04125729

Reaction notes

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