N-bromobutanimide → HCID 54271297, compound

Participants

Reaction Steps

To a solution of 23.3 g of methyl{p-[(p-chlorophenoxy)methoxy]phenyl}acetate in 300 ml of carbon tetrachloride is added 14.2 g of N-bromosuccinimide. The mixture is stirred and refluxed for 24 hours or until reaction is complete. The mixture is cooled, filtered and the filtrate poured through a column of silica gel (60-200 mesh). Cuts (250 ml) are taken with carbon tetrachloride eluent. The product is collected in fractions 2-6 to give 25.5 g of product as an oil.

Provenance & Evidence