Potassium Iodide → HCID 131711331, compound

Participants

Reaction Steps

As described in Example 30, a mixture of 3.13 g of p-tert.-butylphenol, 0.755 g of 60% sodium hydride-oil dispersion, 3.5 g of potassium iodide, one ml of hexamethylphosphoramide and 7.9 g of methyl bromo{p-[3-(p-chlorophenoxy)propoxy]phenyl}acetate in 70 ml of tetrahydrofuran is refluxed for 18 hours and worked-up to give 9.0 g of an oil. The oil is chromatographed over silica gel with dichloromethane as eluent to give 7.4 g of oil which is crystallized from petroleum ether-ether to give 5.7 g of white crystals, mp 98°-101° C.

Provenance & Evidence