5,6,7,8-Tetrahydro-2-naphthol → HCID 86736161, compound

HRID 1704115Notes

Reaction equation

HRID 1704115 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[CH:25]1[C:34]2[CH2:33][CH2:32][CH2:31][CH2:30][C:29]=2[CH:28]=[CH:27][C:26]=1[OH:35]>>[CH3:6][O:5][C:3](=[O:4])[CH:2]([O:35][C:26]1[CH:27]=[CH:28][C:29]2[CH2:30][CH2:31][CH2:32][CH2:33][C:34]=2[CH:25]=1)[C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 143055,6,7,8-Tetrahydro-2-naphtholHCID 22761172HCID 22761172, compound

Product 1

HCID 86736161HCID 86736161, compoundYield 95.6%

Procedure

As described in Example 44, 8.28 g of methyl bromo{p-[3-(p-chlorophenoxy)propoxy]phenyl}acetate is reacted with 3.4 g of 5,6,7,8-tetrahydro-2-naphthol to give 9.2 g of product as a viscous oil.

Sources & evidence

ORD record
ord-3625c839fc5f4156b1f8adf5f72ad938
Source dataset
uspto-grants-1978_11
Patent number
US04125732

Reaction notes

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