4-Cyclohexylphenol → HCID 131711341, compound

HRID 1704116Notes

Reaction equation

Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[CH:25]1([C:31]2[CH:36]=[CH:35][C:34]([OH:37])=[CH:33][CH:32]=2)[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]1>>[CH3:6][O:5][C:3](=[O:4])[CH:2]([O:37][C:34]1[CH:35]=[CH:36][C:31]([CH:25]2[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26]2)=[CH:32][CH:33]=1)[C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)=[CH:9][CH:8]=1

Participants

Reactant 2

HCID 143274-Cyclohexylphenol

HCID 22761172HCID 22761172, compound

Product 1

HCID 131711341HCID 131711341, compoundYield 82.1%

Procedure

As described in Example 44, 8.72 g of methyl bromo{p-[3-(p-chlorophenoxy)propoxy]phenyl}acetate is reacted with 4.05 g of p-cyclohexylphenol to give 8.81 g of product as off-white crystals. Recrystallization from methanol gives white crystals, mp 93°-95° C.

Sources & evidence

ORD record: ord-06cdd14f066046ababaac6547cd5e988
Source dataset: uspto-grants-1978_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04125732

Reaction notes

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