4-Cyclohexylphenol → HCID 131711342, compound

HRID 1704118Notes

Reaction equation

Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[CH:24]1([C:30]2[CH:35]=[CH:34][C:33]([OH:36])=[CH:32][CH:31]=2)[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH3:6][O:5][C:3](=[O:4])[CH:2]([O:36][C:33]1[CH:34]=[CH:35][C:30]([CH:24]2[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]2)=[CH:31][CH:32]=1)[C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[CH:9][CH:8]=1

Participants

Reactant 2

HCID 143274-Cyclohexylphenol

HCID 54245390HCID 54245390, compound

Product 1

HCID 131711342HCID 131711342, compoundYield 86.8%

Procedure

As described in Example 44, 8.0 g of methyl bromo{p-[2-(p-chlorophenoxy)ethoxy]phenyl}acetate is reacted with 4.05 g of p-cyclohexylphenol to give 8.6 g of product as tan crystals. Recrystallization from methanol gives off-white crystals, mp 108°-110° C.

Sources & evidence

ORD record: ord-0b8bab5081cf4114ba9fffe9fa612450
Source dataset: uspto-grants-1978_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04125732

Reaction notes

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