4-(Trifluoromethyl)phenol → HCID 86736163, compound

HRID 1704119Notes

Reaction equation

HRID 1704119 reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[F:24][C:25]([F:34])([F:33])[C:26]1[CH:31]=[CH:30][C:29]([OH:32])=[CH:28][CH:27]=1>>[CH3:6][O:5][C:3](=[O:4])[CH:2]([O:32][C:29]1[CH:30]=[CH:31][C:26]([C:25]([F:24])([F:33])[F:34])=[CH:27][CH:28]=1)[C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][O:16][C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=[CH:9][CH:8]=1

Participants

3

Reactant 2

HCID 678744-(Trifluoromethyl)phenolHCID 54245390HCID 54245390, compound

Product 1

HCID 86736163HCID 86736163, compound

Procedure

As described in Example 44, 8.0 g of methyl bromo{p-[2-(p-chlorophenoxy)ethoxy]phenyl}acetate is reacted with p-trifluoromethylphenol to give 7.4 g of product as white crystals. Recrystallization from methanol gives white crystals, mp 95°-97° C.

Sources & evidence

ORD record
ord-9c201f43512f4c4c9a54c7b96060ca4d
Source dataset
uspto-grants-1978_11
Patent number
US04125732

Reaction notes

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