2-(4-tert-butylphenoxy)propanoic acid → HCID 22761173, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 6.6 g of 2-(p-tert-butylphenoxy)propionic acid in 25 ml of tetrahydrofuran is added dropwise to a chilled (5° C.) solution of 60 ml of 1M diborane in tetrahydrofuran. The mixture is stirred for 1 hr at 5° C. and at room temperature overnight. The mixture is poured onto 300 g of ice-water and extracted with ether. The ether extracts are dried (MgSO4) and concentrated under vacuum to give 5.5 g of product as a colorless liquid.

Provenance & Evidence