HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → HCID 54386710, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Benzeneacetic acid, 4-hydroxy-, methyl ester | HCID 518900 | — |
| Reactant | HCID 20378389 | HCID 20378389 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 54386710 | HCID 54386710 | — |
Reaction Steps
As described in Example 68, 46 g of methyl p-hydroxyphenylacetate is reacted with 2-(p-Fluorophenoxy)-1-propanol O-methane-sulfonate in 400 ml of N,N-dimethylacetamide at 100° C. for 18 hrs. The product is dissolved in 1250 ml of carbon tetrachloride and N-bromosuccinimide added. Anhydrous HBr is added and the mixture is stirred and refluxed for 24 hrs. The mixture is filtered through a short column of silica gel and the solvent removed to give the product as a viscous oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04125732 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-4f210e7120ed47c9addc43265f87b0d2 |
| Source note | uspto-grants-1978_11 |