Potassium Hydroxide → HCID 54251261, compound

Participants

Reaction Steps

9-(3,4-Methylenedioxyphenyl)-6-nonen-2-one [XI; R" is CH3, Ar is 3,4-methylenedioxyphenyl, Y is CH=CHCH2CH2 ] was prepared from 27 g. of ethyl 2-acetyl-8-(3,4-methylenedioxyphenyl)-5-octenoate and potassium hydroxide in aqueous methanol according to the procedure described above in Example 2, part (b). The neutral fraction of the product was chromatographed on 390 g. of activated magnesium silicate and the column was eluted with pentane containing increasing amounts of benzene. The later fractions brought out the desired product, 12.3 g. of 9-(3,4-methylenedioxyphenyl)-6-nonen-2-one.

Provenance & Evidence