Amfenac → Magnesium;bis(2-(2-amino-3-benzoylphenyl)acetate);trihydrate

HRID 1704338Notes

Reaction equation

HRID 1704338 reaction equation
[NH2:1][C:2]1[C:7]([C:8](=[O:15])[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:16][C:17]([OH:19])=[O:18].[Cl-].[Mg+2:21].[Cl-]>>[OH2:15].[OH2:15].[OH2:15].[NH2:1][C:2]1[C:7]([C:8](=[O:15])[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:16][C:17]([O-:19])=[O:18].[Mg+2:21].[NH2:1][C:2]1[C:7]([C:8](=[O:15])[C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][CH:5]=[CH:4][C:3]=1[CH2:16][C:17]([O-:19])=[O:18]

Participants

3

Reactant 2

HCID 2136AmfenacHCID 5360315Magnesium Chloride

Product 1

HCID 12901240Magnesium;bis(2-(2-amino-3-benzoylphenyl)acetate);trihydrate

Procedure

An aqueous solution of 6.36 g. (0.02 mole) of 2-amino-3-benzoylphenylacetic acid was treated with an aqueous solution of magnesium chloride (0.01 mole). A precipitate formed immediately. After 15 min. of stirring, the bright yellow precipitate was filtered and dried. The yield was 4.06 g. and the salt melted over the broad range of 150°-190° C.

Workup

  1. customA precipitate formed immediately
  2. filtrationthe bright yellow precipitate was filtered
  3. customdried
  4. custommelted over the broad range of 150°-190° C.

Sources & evidence

ORD record
ord-dba20a7c1998494f82400df06e86fa65
Source dataset
uspto-grants-1978_11
Patent number
US04126635

Reaction notes

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