HuagongsheHuagongshe Chemistry Print Report · For research reference only
9alpha-Hydroxyandrost-4-ene-3,17-dione → 9-Dehydroandrostenedione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9alpha-Hydroxyandrost-4-ene-3,17-dione | HCID 10425017 | — |
| Solvent | Methanesulfonic Acid | HCID 6395 | — |
| Product | 9-Dehydroandrostenedione | HCID 239595 | — |
Reaction Steps
9α-Hydroxyandrostenedione (.302 g.) is stirred in methanesulfonic acid (3.0 ml.) at 25°. After 80 minutes the reaction is quenched by addition of water (15 ml.). The solids are stirred for 2 hours at 35°, collected, air-dried overnight to give androsta-4,9(11)-diene-3,17-dione, 0.272 g. (95.6% chemical yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04127596 |
| Source dataset | uspto-grants-1978_11 |
| ORD ID | ord-a8e48544200e47a2ab98ede7776c8855 |
| Source note | uspto-grants-1978_11 |