HCID 131711353, compound → HCID 131711351, compound

Participants

Reaction Steps

An 11.0 g portion of the above nitro derivative is hydrogenated in a Parr apparatus with 1.25 g of 10% palladium on carbon and 110 ml of dimethylformamide. The reaction mixture is filtered, concentrated to a small volume and ethanol is added to a total volume of 500 ml. The mixture is concentrated to 100 ml and ether is added. The solid is collected, washed with ether and dried giving 7.8 g of 4-(5-amino-o-toluamido)-5-hydroxy-1,7-naphthalenedisulfonic acid disodium salt.

Provenance & Evidence