反应详情

A mixture of 2.5 g. (0.015 mol) of 3,5-diaminonitrobenzene, 100 ml. of toluene, 15 ml. of acetic acid and 3 ml. (3.24 g., 0.32 mol) of acetic anhydride was refluxed for five hours. The reaction mixture was cooled, filtered and the solid washed well with toluene, then boiled in 150 ml. of ethanol for 20 minutes to give 3,5-bis-acetamidonitrobenzene, m.p.>290° C.

1. additionA mixture of 2.5 g
2. temperatureThe reaction mixture was cooled
3. filtrationfiltered
4. washthe solid washed well with toluene