Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethylamine → Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester, hydrochloride (1:1)
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethylamine | HCID 8021 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 4-Acetamidophenyl chloroacetate | HCID 13277664 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Glycine, N,N-diethyl-, 4-(acetylamino)phenyl ester, hydrochloride (1:1) | HCID 108082 | 39.8% |
반응 단계
22.8 g of p-acetamidophenyl chloroacetate were added in small portions to a solution of 7.5 g of diethylamine in 30 c.c. of triethylamine with stirring, while the temperature was maintained at between 40° C. and 50° C. with a bath of cold water if necessary. The process described in Example 1 was then followed to obtain 12 g of p-acetamidophenyl diethylaminoacetate hydrochloride melting point = 228° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04127671 |
| 출처 데이터셋 | uspto-grants-1978_11 |
| ORD ID | ord-abc1d9f1c5e84e8e9fbe8e110565d271 |
| 출처 메모 | uspto-grants-1978_11 |