Thionyl Chloride → HCID 22758696, compound

HRID 1704742Notes

Reaction equation

HRID 1704742 reaction equation
[C:1]([C:6]1[CH:7]=[CH:8][C:9]([O:15][CH3:16])=[C:10]([CH:14]=1)[C:11](O)=[O:12])(=[O:5])[CH2:2][CH2:3][CH3:4].O=S(Cl)[Cl:19]>>[C:1]([C:6]1[CH:7]=[CH:8][C:9]([O:15][CH3:16])=[C:10]([CH:14]=1)[C:11]([Cl:19])=[O:12])(=[O:5])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 22758695HCID 22758695, compound

Product 1

HCID 22758696HCID 22758696, compoundYield 90%

Conditions

Temperature
30 °C

Procedure

206 g of the acid obtained in Example 4 (0.927 mole), 1 liter of CHCl2, are introduced into a triple-tube flask and 1.11 mole of SOCl2 (80 ml) are added with care. The mixture is maintained for 24 hours at 30° C. and the solvents are then removed. Retreatment with 200 ml of benzene is carried out three times by removing the solvent in vacuo each time. 200 g of the product having a melting point of 65° C. (cyclohexane) are thus obtained with a yield of 90%. IR spectrum (KBr) CO: 1670 and 1780 cm-1.

Workup

  1. customthe solvents are then removed
  2. customby removing the solvent in vacuo each time
  3. customare thus obtained with a yield of 90%

Sources & evidence

ORD record
ord-46f292fc188c455a97170a5cebb6d838
Source dataset
uspto-grants-1978_11
Patent number
US04127666

Reaction notes

Loading…