Aniline → HCID 12901449, compound

HRID 1704753Notes

Reaction equation

HRID 1704753 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br:8][C:9]1[CH:24]=[CH:23][C:12]([CH2:13][N:14]([CH:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)[C:15](Cl)=[S:16])=[CH:11][CH:10]=1>>[Br:8][C:9]1[CH:24]=[CH:23][C:12]([CH2:13][N:14]([CH:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)[C:15]([NH:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[S:16])=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 22758766HCID 22758766, compound

Product 1

HCID 12901449HCID 12901449, compoundYield 80%

Procedure

Analogously to Example 3, 19 grams (0.2 mole) of aniline were reacted with 34 grams (0.1 mole) of N-4-bromobenzyl-N-cyclopentylthiocarbamoyl-chloride, 0.31 grams of N-4-bromobenzyl-N-cyclopentyl-N'-phenylthiourea were obtained. Yield: 80%. Melting point: 129°-131° C.

Sources & evidence

ORD record
ord-2a86537030aa4bcdbb358ea90661eee6
Source dataset
uspto-grants-1978_11
Patent number
US04127673

Reaction notes

Loading…