N,N-Dimethyl-1,3-propanediamine → HCID 22758500, compound

HRID 1704757Notes

Reaction equation

HRID 1704757 reaction equation
[CH3:1]C(N)CC.CN(C)CCCN.CN(C)[CH2:15][CH2:16][CH2:17][NH:18][C:19]1[C:24]2[CH:25]=[N:26][C:27]3[N:31]([CH2:32][CH3:33])[N:30]=[CH:29][C:28]=3[C:23]=2[N:22]2[N:34]=[CH:35][N:36]=[C:21]2[N:20]=1>>[CH2:32]([N:31]1[C:27]2[N:26]=[CH:25][C:24]3[C:19]([NH:18][CH:17]([CH3:1])[CH2:16][CH3:15])=[N:20][C:21]4[N:22]([N:34]=[CH:35][N:36]=4)[C:23]=3[C:28]=2[CH:29]=[N:30]1)[CH3:33]

Participants

4

Reactant 3

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 24874Sec-ButylamineHCID 22758490HCID 22758490, compound

Product 1

HCID 22758500HCID 22758500, compoundYield 78%

Procedure

By substituting 1-methylpropylamine for the 3-dimethylaminopropylamine in the procedure of Example 1 (c), 8-ethyl-N-(1-methylpropyl)-8H-pyrazolo[4',3':5,6]pyrido[3,4-e]-[1,2,4]triazolo[1,5-a]pyrimidin-5-amine is obtained, yield 78%; m.p. 228°-230° (methanol).

Sources & evidence

ORD record
ord-c32ca41045e74cdba1bd05c88e9f101f
Source dataset
uspto-grants-1978_11
Patent number
US04127655

Reaction notes

Loading…