Benzoyl chloride → 8-Benzoyl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

HRID 1704763Notes

Reaction equation

HRID 1704763 reaction equation
[C:1]1([O:7][C:8]2[C:13]3[CH:14]=[N:15][C:16]4[NH:20][N:19]=[CH:18][C:17]=4[C:12]=3[N:11]3[N:21]=[CH:22][N:23]=[C:10]3[N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:24](Cl)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>N1C=CC=CC=1>[C:24]([N:20]1[C:16]2[N:15]=[CH:14][C:13]3[C:8]([O:7][C:1]4[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=4)=[N:9][C:10]4[N:11]([N:21]=[CH:22][N:23]=4)[C:12]=3[C:17]=2[CH:18]=[N:19]1)(=[O:31])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1

Participants

4

Reactant 2

HCID 7412Benzoyl chlorideHCID 178420510HCID 178420510, compound

Product 1

HCID 227585058-Benzoyl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

0.01 mol. of 5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido-[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine and 0.02 mol. of benzoyl chloride are stirred overnight in 50 ml. of dry pyridine at room temperature. On addition of 50 ml. of water, 8-benzoyl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido-[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine is filtered off.

Workup

  1. customat room temperature
  2. additionOn addition of 50 ml
  3. filtrationof water, 8-benzoyl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido-[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine is filtered off

Sources & evidence

ORD record
ord-43bcfb6b57364ba492e7765766ce3e61
Source dataset
uspto-grants-1978_11
Patent number
US04127655

Reaction notes

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