N,N-Dimethyl-1,3-propanediamine → 8-Ethyl-5-(1-pyrrolidinyl)-8H-pyrazolo[4',3':5,6]-pyrido-[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

HRID 1704766Notes

Reaction equation

HRID 1704766 reaction equation
C[N:2]([CH3:7])[CH2:3][CH2:4][CH2:5]N.[C:8]([N:16]1[C:20]2[N:21]=[CH:22][C:23]3[C:24](OC4C=CC=CC=4)=[N:25][C:26]4[N:27]([N:29]=[CH:30][N:31]=4)[C:28]=3[C:19]=2[CH:18]=[N:17]1)(=O)[C:9]1C=CC=CC=1.N1(N2N3C4C5C=NNC=5N=CC=4C=NC3=NC2)CCCC1>>[CH2:8]([N:16]1[C:20]2[N:21]=[CH:22][C:23]3[C:24]([N:2]4[CH2:3][CH2:4][CH2:5][CH2:7]4)=[N:25][C:26]4[N:27]([N:29]=[CH:30][N:31]=4)[C:28]=3[C:19]=2[CH:18]=[N:17]1)[CH3:9]

Participants

4

Reactant 3

HCID 7993N,N-Dimethyl-1,3-propanediamineHCID 227585058-Benzoyl-5-phenyloxy-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidineHCID 178420867HCID 178420867, compound

Product 1

HCID 227585368-Ethyl-5-(1-pyrrolidinyl)-8H-pyrazolo[4',3':5,6]-pyrido-[3,4-e][1,2,4]triazolo[1,5-a]pyrimidine

Procedure

By substituting pyrrolidine for 3-(dimethylamino)propylamine in the procedure of Example 1 (c), 8-ethyl-5-(1-pyrrolidinyl-8H-pyrazolo[4',3':5,6]pyrido[3,4-e][1,2,4]-triazolo[1,5-a]pyrimidine is obtained.

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-41571e751e27442ebe6b26c3ae6b702b
Source dataset
uspto-grants-1978_11
Patent number
US04127655

Reaction notes

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