HCID 18785781, compound → HCID 22758828, compound

Participants

Reaction Steps

A stirred mixture of (±)-1-amino-4-ethyl-3,4-dihydroisoquinoline (6.83 g.) and 10% palladium on carbon (1.5 g.) in p-cymene (80 ml.) was refluxed for 4 hours. The mixture was filtered and the filtrate reduced to dryness in vacuo to leave an oil which when crystallized successively from Skellysolve B and cyclohexane gave 1.84 g. (27% yield) of the product, m.p. 84°-85°.

Provenance & Evidence