1-[2-Fluoro-4-(methylsulfonyl)phenyl]piperazine → [4-(2-Fluoro-4-methanesulfonyl-phenyl)-piperazin-1-yl]-(2-iodo-5-methanesulfonyl-phenyl)-methanone
Reaction equation
[F:15][c:16]1[c:17]([N:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:18][cH:19][c:20]([S:22](=[O:23])(=[O:24])[CH3:25])[cH:21]1.[I:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([S:11](=[O:12])(=[O:13])[CH3:14])[cH:9][cH:10]1>>[I:1][c:2]1[c:3]([C:4](=[O:6])[N:29]2[CH2:28][CH2:27][N:26]([c:17]3[c:16]([F:15])[cH:21][c:20]([S:22](=[O:23])(=[O:24])[CH3:25])[cH:19][cH:18]3)[CH2:31][CH2:30]2)[cH:7][c:8]([S:11](=[O:12])(=[O:13])[CH3:14])[cH:9][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-32b1a7ad0eae413ca73958706ac035ef
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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