HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloro-N,N-dimethyl-1-propanamine → HCID 20336504, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloro-N,N-dimethyl-1-propanamine | HCID 66960 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 4-Benzyl-6-methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol | HCID 12940906 | — |
| Product | HCID 20336504 | HCID 20336504 | 106.8% |
Reaction Steps
12.1 g (50 millimoles) of 4-benzyl-6-methyl-1,3-dihydro-furo[3,4-c]pyridin-7-ol are converted to the sodium salt as described in Example 1 (a) and reacted with 9.2 g (75 millimoles) of N-(3-chloropropyl)-N,N-dimethylamine. Working up as described in Example 1 (a) gives 16.0 g of 4-benzyl-6-methyl-1,3-dihydro-furo[3,4-c]pyridin-7-yl 3-dimethylaminopropyl ether bis-hydrochloride, which is recrystallized from isopropanol/ethanol; melting point 202°-204° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04206117 |
| Source dataset | uspto-grants-1980_06 |
| ORD ID | ord-4b5bf379f6c14164bb0d7cfc7b08832f |
| Source note | uspto-grants-1980_06 |