Toluene → HCID 70592776, compound

Participants

Reaction Steps

26 g of 3-(4-chloromethylphenyl)-1,2-benzisothiazole, 6.4 g of sulfur and 300 ml of toluene are heated to 50° C. and 12 g of ethylenediamine are added slowly at this temperature. The reaction mixture is then stirred for 15 hours under reflux and is filtered hot, and the filtrate is cooled to 10°-15° C. 21 g of 3-(4-imidazolin-2-yl-phenyl)-1,2-benzisothiazole, melting at 177° C., are obtained. This corresponds to a yield of 75% of theory.

Provenance & Evidence