Ethylenediamine → HCID 23453958, compound

Participants

Reaction Steps

44 g of 5-chloro-3-(4'-chloromethylphenyl)-1,2-benzisothiazole, 9.6 g of sulfur and 18 g of ethylenediamine in 500 ml of toluene are refluxed for 20 hours. The reaction mixture is filtered hot, the filtrate is cooled and the resulting crystals are filtered off. After recrystallization from toluene in the presence of active charcoal, 26 g of 5-chloro-3-[4-(imidazolin-2-yl)-phenyl]-1,2-benzisothiazole, melting at 195° C., are obtained. The yield corresponds to 55% of theory.

Provenance & Evidence