HCID 20337447, compound → HCID 86737026, compound

Participants

Reaction Steps

To a solution of 1.0 g. of dl-7,8,9,10-tetrahydro-2-hydroxy-6,6-dimethyl-3-(1-methyl-4-phenylbutyl)-6H-dibenzo[b,d]pyran in 75 ml. of ethanol is added 200 mg. of 5% palladium-on-carbon catalyst and the resulting mixture is hydrogenated at room temperature and 60 psig. (4.3 kg./cm2) until the theoretical amount of hydrogen is consumed. After filtering to remove the catalyst, the solvent was evaporated to provide the desired 6a,10a-cis compound.

Provenance & Evidence